There are a number of drugs that require nursing assessment at various intervals during their infusion; example:  Rituximab (RITUXAN) , Immune Globulin, and infliximab (REMICADE). With each of these agents, tolerance to infusion and detection of infusion related side effects are essentials of the drug’s administration.

These infusion issues are typically met by starting the infusion as a low rate and running it in over a defined period of time. At the end of the time, a nursing assessment is performed and if the patient is experiencing no infusion related complications, the infusion rate is increased by a defined rate and a new infusion interval is established for the next nursing assessment.

Taking Rituximab as an example, the following information is included in the package insert under the heading of First Administration: “First Infusion:  Initiate infusion at a rate of 50 mg/hr. In the absence of infusion toxicity, increase infusion rate by 50 mg/hr increments every 30 minutes, to a maximum of 400 mg/hr.” Nursing must, at each 50 mg / hr level, assess patient tolerance to the medication and observe for administration related issues. has designed a label that can be easily printed by the pharmacy (or nursing) and affixed to the infusion solution providing nursing with this important information.

The label features include:

  • Patient demographic information
  • Total dose (600 mg)
  • Final Volume (dose volume [60 mL] + diluent volume [500 mL]
  • Concentration (dose [600 mg] / volume [560 mL])
  • Concentration parameters (1 — 4 mg / mL)
  • Dose administration intervals (50 mg / hr — 400 mg / hr)
  • Dose administration nursing assessment intervals (30 minutes)
  • Calculation of VTBI (volume to be infused). By calculating this value, we eliminate the requirement for any nursing bedside calculations. The VTBI is entered into the “smart pump” at each assessment interval. This allows nurse to spend more time with patient. The VTBI calculation is specific for each dose.
  • Preparation date / time
  • Beyond Use date / time
  • Exclusive to RxTOOLKIT Labels, our QR code with a direct link to the most current package insert for the drug
Rituximab Initial Infusion Label

Rituximab (RITUXAN) Initial Infusion Dose Label

All the information on this label is generated by entering just 3 data elements in the label prompt screen:

  1. Patient Name (optional)
  2. Patient MRN (optional)
  3. Dose (mg)

We have a similar label for the Rituximab 90 minute infusion as well as labels for the drugs listed above. This label prints on as a direct thermal or thermal transfer Zebra printer using a popular 4 x 3 inch label.

We can customize any label design for any drug.

RxTOOLKIT calculates for nursing and breaks down the barriers to patient focused care:

  • Focus on patient needs not equipment needs
  • Let Smart pumps tell you when patient needs vital sign check
  • Calculations are no longer a distraction from patients

When nurses spend time calculating infusion titration rates and trying to remember on their own when to check their patients vital signs they lose time they could be focusing on the patient. RxTOOLKIT can increase the IQ of your smart pump by performing the calculations for you.

Titrating Infusion Drip Rates

Vital Sign / Patient Assessment Times

Patient focused care has taken center stage since the Patient Protection and Affordable Care Act was signed into law (March 2010). The Patient Protection and Affordable Care Act includes a value-based purchasing (VBP) initiative. This focuses on a Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) and measures core results based on patient satisfaction surveys. Allowing nurses more time to focus on their patients can increase patient satisfaction and now also has the potential to increase critical funding for your organization.

Please visit RxTOOLKIT Labels to learn more about this and our other labeling solutions.


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